A natural compound found in apple could help us slow down aging, a new research suggests. It has identified a compound in many types of fruit including apples, vegetables, and strawberries that can slow aging.
The factor which plays a key role in the aging process is called “cellular senescence,” or the aging of the cell. When this process starts, a cell ceases to divide. The number of senescent cells in tissues increases substantially during the aging.
Prof. Paul D. Robbins, from the University of Minnesota teamed up with scientists at the University of Minnesota Medical School in Minneapolis and the Mayo Clinic in Rochester, MN, to find out which senolytics can help slow down the aging processes. Their new findings are published in the journal EBioMedicine.
During the latest research, the investigators tested 10 flavonoids, a diverse group of compounds found in almost all fruits and vegetables, in aging mice. One of the most effective compounds that they found was fistein which comes naturally in many fruits and vegetables such as apples, onions, cucumbers, and strawberries. When they treated aging mice with fistein, they found a reduction of senescent cells levels in the animal. It also extended animals’ lifespan and boosted health.
“These results suggest that we can extend the period of health, termed healthspan, even towards the end of life,” explains Prof. Robbins.
“In addition to showing that the drug works, this is the first demonstration that shows the effects of the drug on specific subsets of these damaged cells within a given tissue.”