Can probiotics help people with osteoporosis fight bone loss? Osteoporosis is a bone disease that occurs when body losses bone density and it can begin at as early as age 40. In the latest study, researchers found that probiotics might help protect bone health without causing side effects.
Bone is made up of living tissue and actively constructed and remodeled throughout life. The body stops the process of increasing bone mass by around age 30 and at the age of 40 and 50, more broken bones can occur. This can cause osteoporosis and lead to fractures.
Other risk factors including smoking tobacco, getting early menopause, having a family history of osteoporosis, and having a smaller body frame may also cause bone break by the age of 50.
Now the latest study, led by senior study author Roberto Pacifici — of Emory University in Atlanta, GA, analyzed the effect of a probiotic on bone health. It now appears in the journal Immunity.
The researchers orally gave Lactobacillus rhamnosus GG supplementation to female laboratory mice for a period over 4 weeks.
The team found that the probiotic led to developing a particular metabolite called butyrate which then caused T cells in bone marrow to make Wnt10b. It’s a protein which is important for bone growth.
“We were surprised by the potency of the gut microbiome in regulating bone and by the complexity of the mechanism of action of probiotics,” said senior study author Roberto Pacifici from Emory University in Atlanta, GA.